The relationship between the Kardashian family and Lamar Odom has gotten progressively rocky since his split from his ex-wife Khloé. Any hopes of a reconciliation between the former NBA star and is former in-laws appear to be long gone after shade from his ex sister-in-law, Kim Kardashian.

The drama began after Odom’s appearance on the inaugural episode of BET’s new late-night talk show, Mancave. When asked about his ex-wife’s new pregnancy with boyfriend Tristan Thompson, Odom said, “She took care of me. She’ll be a good mother, for real. She’s a great woman.”

“I understand when it’s over, it’s over. When [Khloé] was with her second or third NBA ball player, I could see that,” Odom added.

Once word of Odom’s comments went viral, the KKW beauty founder quickly hopped on Twitter with a few harsh words for her former in-law.

Kardashian’s harsh comments allude to Odom’s frightening 2015 experience where he was found unconscious in a Nevada brothel. Odom, who couldn’t speak when he first regained consciousness, was hospitalized for three months before he was released.

While Khloé Kardashian didn’t make an official response, she issued a subtle co-sign liking her big sister’s tweet.

Social media quickly came to Kim Kardashian’s defense following her shady tweets.

Check out Twitter reactions to Kim Kardashian’s Lamar Odom shade below: